Covid
Ramesh Baradaran Bagheri
Abstract
Introduction: TXA may lessen the need for hysterectomy, lessen the risk of developing severe anemia, and prevent the need for blood transfusions, all of which could significantly advance the objective of lowering maternal mortality, according to several RCTs that have examined the prophylactic role of ...
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Introduction: TXA may lessen the need for hysterectomy, lessen the risk of developing severe anemia, and prevent the need for blood transfusions, all of which could significantly advance the objective of lowering maternal mortality, according to several RCTs that have examined the prophylactic role of the drug (described in the discussion). Material and Methods: To make TXA injection, 1 gram (10ml) of TXA was diluted in 100ml of sterile saline. To those in the study group, TXA was infused intravenously for more than 15 minutes, at least 20 minutes before making a skin incision. The control group received no medication at all. All of the participants received spinal anesthesia. Surgery was performed by assistant professors with an MD degree and at least three years of experience. Results: Primary outcomes included blood loss from placental delivery to the conclusion of surgery and the percentage of hemoglobin difference, while secondary outcomes included the length of surgery and the percentage of patients who lost more than 500 ml of blood. There was a significant difference between the two groups in these primary and secondary outcomes. Conclusion: TXA significantly decreased the amount of blood lost during LSCS. Being in a hypercoagulable state during pregnancy increases the risk of thrombotic events. However, there were no negative side effects or complications in the first few weeks after delivery when this antifibrinolytic was used. So, when subjects are undergoing LSCS, TXA can be applied effectively and safely.
Health
Ramesh Baradaran Bagheri
Abstract
Introduction: According to information currently available, there has not yet been a published study about the effectiveness of intraperitoneal dexamethasone that uses high-quality methodology. However, after laparoscopy, dexamethasone intravenously has been used to treat nausea. In this study, we compare ...
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Introduction: According to information currently available, there has not yet been a published study about the effectiveness of intraperitoneal dexamethasone that uses high-quality methodology. However, after laparoscopy, dexamethasone intravenously has been used to treat nausea. In this study, we compare the efficacy of intraperitoneal dexamethasone with placebo in patients who have undergone gynecologic laparoscopy in a double-blind randomized clinical trial.Material and Methods: The patients were divided into groups using the four-block block randomization method. The groups' treatment options were chosen at random by drawing lots. There were an equal number of candidates in each block at the conclusion of the selection process. Anesthesia was administered to each patient. A 16 mg dose of dexamethasone was administered into the peritoneum of patients in the first group at the conclusion of the procedure, while patients in the second group received a placebo injection of 16 cc of normal saline.Results: Within the first 0, 2, 4, 8, and 12 hours following the procedure, the dexamethasone group experienced significantly less pain than the placebo group. The placebo group consumed more opioids on average as analgesics/sedatives than the dexamethasone group. Conclusion: Our study's findings demonstrate that, compared to a placebo, 16 mg of dexamethasone can significantly lessen the intensity of pain following gynecologic laparoscopy, and these patients also require fewer opioids. Controlling postoperative pain following laparoscopic surgery can be done in advance using this technique, which has no negative side effects.
Health
Mehrdad Zamani Esfahlani; Ramesh Baradaran Bagheri
Abstract
Introduction: A woman's body undergoes physiological and anatomical changes during pregnancy that affect a number of systems, including the musculoskeletal system. These alterations may result in low back pain or low pelvic pain during or after pregnancy, impairing the movement of these structures and ...
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Introduction: A woman's body undergoes physiological and anatomical changes during pregnancy that affect a number of systems, including the musculoskeletal system. These alterations may result in low back pain or low pelvic pain during or after pregnancy, impairing the movement of these structures and causing discomfort. Material and methods: Using the terms "low back pain," "pelvic girdle pain," "lumbopelvic pain," "posterior pelvic pain," "pregnancy-related low back pain," "pregnancy-related pelvic girdle pain," and "pregnancy-related lumbopelvic pain," we searched the literature in Pubmed, Cochrane Library, Ovid, and Google for articles in English, Portuguese, and Spanish published in the previous 20 years or older, as appropriate. Results: In this study we focus on terminology, epidemiology, risk factors, pathophysiology, prognosis, diagnosis, and treatment, the aim of this study was to discuss the diagnosis and treatment of pregnancy-related lumbosacral pain. Conclusion: One of the main causes of lumbosacral pain is pregnancy, which is also one of the most common illnesses during gestation. Pregnant women's quality of life is improved when this pathology is properly managed.
Medicine
Ramesh Baradaran Bagheri
Abstract
Introduction: The common perception that this treatment has no serious side effects is probably influenced by this flawed evidence. In this large population-based study, our goals were to determine whether there was an independent relationship between the amount of oxytocin exposed during labor and the ...
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Introduction: The common perception that this treatment has no serious side effects is probably influenced by this flawed evidence. In this large population-based study, our goals were to determine whether there was an independent relationship between the amount of oxytocin exposed during labor and the risk of developing severe PPH and to determine whether the prophylactic use of oxytocin after delivery affected this relationship. Material and Methods: women who had straightforward pregnancies and delivered term singletons vaginally. Cases were 1483 women with severe PPH, which was indicated by peripartum hemoglobin changes of less than 4 g/dl or the requirement for blood transfusions. 90 women from a randomly selected group of expectant mothers without PPH served as the controls. Using two-level multivariable logistic regression modeling, the independent relationship between the oxytocin level during labor and the risk of developing severe PPH was examined and quantified with ORs. Results: After adjusting for all possible confounders, oxytocin exposure during labor was linked to a higher risk of severe PPH when prophylactic oxytocin was not given after delivery. With more oxytocin injected, the association became stronger. The risk of severe PPH was approximately three times higher for total doses between 2 and 4 IU and six times higher for total doses over 4 IU. Conclusion: A separate risk factor for severe PPH appears to be oxytocin during labor. Our findings add to the body of evidence highlighting the need for precautions to reduce maternal complications when oxytocin is used to speed up labor, including strict indications, the use of the lowest effective dose, and careful efficacy evaluation.
Covid
Sanaz Yasrebi; Ramesh Baradaran Bagheri
Abstract
Introduction: The analysis of a cohort of patients during the embryo transfer phase was the main focus of this study. The aim of the study was to examine the effects of thirteen adjuvant therapies on the success of embryo transfer, including the clinical pregnancy and live birth rates with enoxaparin. ...
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Introduction: The analysis of a cohort of patients during the embryo transfer phase was the main focus of this study. The aim of the study was to examine the effects of thirteen adjuvant therapies on the success of embryo transfer, including the clinical pregnancy and live birth rates with enoxaparin. Materials and Method: A random number was applied to each transfer in order to ensure data independence, and it was then used to select a single transfer for each patient while erasing the other 90 duplicate cycles. Gonadotropin stimulation was either downregulated or gonadotrophin antagonist stimulation—with or without pre-treatment with the oral contraceptive pill—was used to stimulate. Vitrification was used to freeze the embryos. Results: 16 known seropositive IVF implantation failure patients had 25 additional transfers of 47 embryos, resulting in two clinical pregnancies (fetal heart implantation rate, 42%). These patients did not want to participate in the trial and did not receive heparin and aspirin from their treating physician. Conclusion: A large number of the interventions examined in this study fall short of demonstrating any effects on the success of embryo transfers. According to the findings of our analysis enoxaparin use has shown promising, possibly advantageous results.
Covid
Ramesh Baradaran Bagheri
Abstract
Introduction: This review addresses some of the issues that doctors encounter when treating a brain tumor in a patient who is pregnant, with a focus on radiation oncology viewpoints. Pregnancy and its effects on cancer survivors are outside the purview of this discussion.Material and Methods: Using the ...
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Introduction: This review addresses some of the issues that doctors encounter when treating a brain tumor in a patient who is pregnant, with a focus on radiation oncology viewpoints. Pregnancy and its effects on cancer survivors are outside the purview of this discussion.Material and Methods: Using the terms " brain " " tumors" " brain tumors " " pregnancy " "pregnancy-related brain tumors " "pregnancy-related tumors " and " brain tumors in pregnancy " we searched the literature in Pubmed, Cochrane Library, Ovid, and Google for articles in English, Portuguese, and Spanish published in the previous 20 years or older, as appropriateResults: Since there are no established management guidelines and there are numerous moral and ethical conundrums, the link between brain tumors and pregnancy presents a difficult challenge for the management team. Only small retrospective series of literature are currently available. It is necessary to develop a multidisciplinary plan with individualized management and thorough patient and family counseling at every stage. Conclusion: This task should only be taken on by large centers with the resources to manage every aspect of therapy related to obstetrics, neonatology, and oncology. The creation of central registries might improve data collection and interpretation to inform future strategies.
Health
Ali Alahgholi; Ramesh Baradaran Bagheri
Abstract
Introduction: This review aimed to describe pregnancy-related hand and wrist issues and provide an overview of the pathology, clinic presentations, clinical examinations, and treatment options for these conditions; however, it does not discuss autoimmune-related musculoskeletal disorders during pregnancy. ...
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Introduction: This review aimed to describe pregnancy-related hand and wrist issues and provide an overview of the pathology, clinic presentations, clinical examinations, and treatment options for these conditions; however, it does not discuss autoimmune-related musculoskeletal disorders during pregnancy. Material and Methods: Using the terms " Hand," " Wrist," " Hand and Wrist," " Hand and Wrist problem " "pregnancy-related Hand pain," "pregnancy-related Wrist pain," and "pregnancy-related Hand and Wrist pain," we searched the literature in Pubmed, Cochrane Library, Ovid, and Google for articles in English, Portuguese, and Spanish published in the previous 20 years or older, as appropriate. Results: The quality of life for pregnant women who have hand and wrist issues may be reduced. These ailments are temporary, benign, and self-limiting, and it is anticipated that they will go away after giving birth. Conclusion: During the third trimester of pregnancy, when hormonal changes, fluid retention, and weight gain are at their peak, hand and wrist problems are most common. Although NA, pyogenic granuloma in the hand, ligamentous laxity of the joints, arthralgia, and exacerbation of arthritis in the hand and wrist have all been reported, the most common disorders are pregnancy-related CTS and De Quervain disease. For problems with the hands and wrists caused by pregnancy, non-surgical treatments are frequently successful.
Health
Ali Alahgholi; Ramesh Baradaran Bagheri
Abstract
Introduction: The severity of the symptoms and the risk factors connected to them have not been described, but knee pain can be a common complaint during pregnancy. The purpose of this study was to identify knee-related dysfunction in a general obstetric population and to list risk factors. Material ...
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Introduction: The severity of the symptoms and the risk factors connected to them have not been described, but knee pain can be a common complaint during pregnancy. The purpose of this study was to identify knee-related dysfunction in a general obstetric population and to list risk factors. Material and Methods: In this systematic review, Patients in obstetric clinics completed the Pregnancy Physical Activity Questionnaire (PPAQ), a validated instrument to measure physical activity, as well as the International Knee Documentation Committee (IKDC) questionnaire to assess their knee function. To find independent associations with IKDC score and identify predictors of knee dysfunction, analyses of age, weeks of gestation, height, weight, and history of knee issues prior to pregnancy were performed. Results: A mean PPAQ score of 248 MET-h/wk, with a range of 40 to 805 MET-h/wk, was used to estimate physical activity in the study population. With no discernible differences between trimesters (7.3 percent, 6.3 percent, and 6.1 percent in the first, second, and third trimester groups, respectively), twenty (6.5 percent) women reported having a PPAQ greater than 500 MET-h/wk. Seventy-six (24%) of the women in this study reported a history of knee surgery, an injury, or other knee issue. Conclusion: A high level of activity, younger age, higher BMI, and a history of knee problems were all associated with severe knee dysfunction, which was reported by 26.1% of pregnant women. These findings might have consequences for pregnant women who want to stay active and fit during their training. Future research is advised to evaluate the need for intervention and to determine the best ways to prevent and treat symptoms in this population.
